The Department of Statistics, created along with IME in 1970, brings together researchers from the areas of Probability and Statistics, and is responsible for courses and disciplines in Graduation, Improvement and Post-Graduation. The department offers the Bachelor of Statistics, at the undergraduate level, the Improvement Topics in Statistics at the level of refinement, and a Masters in Statistics and Ph.D. in Statistics at the graduate level.

The Statistics Department also contributes to other disciplines and programs at IME USP: basic disciplines of Probability and Statistics, offered to the whole USP, and other, more advanced, for specific courses, and advisory services to researchers from USP and other institutions.